Job Description
Yoh is hiring a highly motivated and skilled
Senior Research Scientist, Computational Biology for our South San Francisco, CA client. This role offers a unique opportunity to contribute to both early- and late-stage drug discovery programs through advanced computational analyses.
Industry : Discovery and Research
Location : South San Francisco, CA
Compensation : $65-85/hr (based upon experience)
Type : Contract / On-site (full-time)
Job Functions: - Lead and support computational investigations across the drug discovery pipeline, including: Biomarker discovery for late-stage programs; and Target identification and mechanism of action studies for early-stage programs.
- Analyze and interpret multi-omics and CRISPR screening datasets from internal and public sources to elucidate drug mechanisms.
- Collaborate closely with cross-functional teams to test hypotheses and accelerate research through data-driven insights.
- Present findings clearly and effectively to project teams and broader scientific audiences.
- Develop a strong understanding of the cancer biology relevant to therapeutic programs to enhance analytical impact.
Preferred Qualifications: - Proficiency in analyzing diverse omics data types (e.g., transcriptomics, proteomics, metabolomics) from in vitro, in vivo, and clinical sources.
- Experience with:
- Whole genome/exome sequencing (WGS/WES), including mutation calling and variant annotation.
- Functional genomics datasets, particularly CRISPR screens.
- Oncology-focused datasets and resources such as TCGA, DepMap, and others.
- Non-NGS omics platforms (e.g., Mass Spec, Olink, Nanostring).
- Familiarity with machine learning techniques for multi-omics integration and predictive modeling.
- Knowledge of non-linear modeling, optimization, Bayesian methods, and causal inference approaches.
- Strong technical skills in R, Python, & JavaScript, with a strong foundation in biology and hands-on laboratory experience.
- Comfort working with local or commercial large language models (LLMs) and integrating them into analytical workflows.
- Strong coding practices, including version control and software engineering principles.
Estimated Min Rate : $59.50
Estimated Max Rate : $85.00
Note: Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply.
Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
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For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship, potentially resulting in the withdrawal of a conditional offer of employment.
Job Tags
Full time, Contract work, Local area,